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Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice.
Zhou, Libin; Flores, Joseph; Noël, Anastasia; Beauchet, Olivier; Sjöström, P Jesper; LeBlanc, Andrea C.
Afiliação
  • Zhou L; Lady Davis Institute for Medical Research at Jewish General Hospital, 3999 Ch. Côte Ste-Catherine, Montreal, QC, H3T 1E2, Canada.
  • Flores J; Department of Anatomy and Cell Biology, McGill University, 3640 University Street Strathcona Anatomy Building, Montreal, QC, H3A 0C7, Canada.
  • Noël A; Lady Davis Institute for Medical Research at Jewish General Hospital, 3999 Ch. Côte Ste-Catherine, Montreal, QC, H3T 1E2, Canada.
  • Beauchet O; Lady Davis Institute for Medical Research at Jewish General Hospital, 3999 Ch. Côte Ste-Catherine, Montreal, QC, H3T 1E2, Canada.
  • Sjöström PJ; Lady Davis Institute for Medical Research at Jewish General Hospital, 3999 Ch. Côte Ste-Catherine, Montreal, QC, H3T 1E2, Canada.
  • LeBlanc AC; Department of Medicine, Division of Geriatric Medicine, Sir Mortimer B. Davis - Jewish General Hospital, 3999 Ch. Côte Ste-Catherine, Montreal, QC, H3T 1E2, Canada.
Acta Neuropathol Commun ; 7(1): 210, 2019 12 16.
Article em En | MEDLINE | ID: mdl-31843022
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Caspase 6 / Disfunção Cognitiva / Inibidores de Caspase / Azul de Metileno Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Caspase 6 / Disfunção Cognitiva / Inibidores de Caspase / Azul de Metileno Idioma: En Ano de publicação: 2019 Tipo de documento: Article