Tanshinone IIA Ameliorates CNS Autoimmunity by Promoting the Differentiation of Regulatory T Cells.

Gong, Ye; Liu, Yuan-Chu; Ding, Xiao-Li; Fu, Ying; Cui, Lang-Jun; Yan, Ya-Ping

Gong, Ye; Liu, Yuan-Chu; Ding, Xiao-Li; Fu, Ying; Cui, Lang-Jun; Yan, Ya-Ping.

Afiliação

Gong Y; Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710000, China.
Liu YC; Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710000, China.
Ding XL; Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710000, China.
Fu Y; Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710000, China.
Cui LJ; Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710000, China. ljcui@snnu.ed
Yan YP; , Xi'an, China. ljcui@snnu.edu.cn.

Neurotherapeutics ; 17(2): 690-703, 2020 04.

Article em En | MEDLINE | ID: mdl-31845175

Assuntos

Abietanos/farmacologia; Diferenciação Celular/efeitos dos fármacos; Encefalomielite Autoimune Experimental/imunologia; Imunossupressores/farmacologia; Linfócitos T Reguladores/efeitos dos fármacos; Animais; Autoimunidade/efeitos dos fármacos; Autoimunidade/imunologia; Diferenciação Celular/imunologia; Encefalomielite Autoimune Experimental/patologia; Feminino; Camundongos; Camundongos Endogâmicos C57BL; Medula Espinal/efeitos dos fármacos; Medula Espinal/imunologia; Medula Espinal/patologia; Linfócitos T Reguladores/imunologia

Palavras-chave

Tanshinone IIA (TSA); Treg cell; experimental autoimmune encephalomyelitis (EAE); multiple sclerosis (MS); transforming growth factor ß1 (TGF-ß1)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Linfócitos T Reguladores / Abietanos / Encefalomielite Autoimune Experimental / Imunossupressores Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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