<i>In vitro</i> detection of haematogenous prions in white-tailed deer orally dosed with low concentrations of chronic wasting disease.

McNulty, Erin E; Nalls, Amy V; Xun, Randy; Denkers, Nathaniel D; Hoover, Edward A; Mathiason, Candace K

In vitro detection of haematogenous prions in white-tailed deer orally dosed with low concentrations of chronic wasting disease.

McNulty, Erin E; Nalls, Amy V; Xun, Randy; Denkers, Nathaniel D; Hoover, Edward A; Mathiason, Candace K.

Afiliação

McNulty EE; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Nalls AV; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Xun R; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Denkers ND; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Hoover EA; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Mathiason CK; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.

J Gen Virol ; 101(3): 347-361, 2020 03.

Article em En | MEDLINE | ID: mdl-31846418

Assuntos

Cervos/sangue; Proteínas PrPC/genética; Proteínas PrPC/metabolismo; Doença de Emaciação Crônica/patologia; Amiloide/metabolismo; Animais; Encéfalo/metabolismo; Encéfalo/patologia; Estudos de Coortes; Estudos Longitudinais; Mesocricetus; Camundongos; Camundongos Transgênicos; Reação em Cadeia da Polimerase em Tempo Real/métodos; Saliva/metabolismo

Palavras-chave

Haematogenous prions; PMCA; RT-QuIC; in vitro prion detection; prionemia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cervos / Proteínas PrPC / Doença de Emaciação Crônica Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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