Preparation of hemoglobin (Hb)-imprinted poly(ionic liquid)s via Hb-catalyzed eATRP on gold nanodendrites.
Anal Bioanal Chem
; 412(4): 983-991, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31848668
Hemoglobin (Hb)-imprinted poly(ionic liquid)s (HIPILs) were prepared on the surface of Au electrode modified with gold nanodendrites (Au/ND/HIPILs). HIPILs were synthesized with 1-vinyl-3-propyl imidazole sulfonate ionic liquids as functional monomers via electrochemically mediated atom transfer radical polymerization (eATRP) catalyzed by Hb. The Au/ND/HIPILs electrode was examined by cyclic voltammetry (CV), scanning electron microscope (SEM), and X-ray photoelectron spectroscopy (XPS). The Au/ND/HIPILs electrode was also used as an electrochemical sensor to determine Hb by differential pulse voltammetry (DPV). Under the optimal conditions, the detection range of Hb was from 1.0 × 10-14 to 1.0 × 10-4 mg/mL with a limit of detection of 5.22 × 10-15 mg/mL (S/N = 3). Compared with other methods, the sensor based on poly(ionic liquid)s had the broader linear range and lower detection limit. Graphical Abstract.
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MEDLINE
Assunto principal:
Hemoglobinas
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Líquidos Iônicos
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Nanopartículas Metálicas
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Impressão Molecular
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Ouro
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article