Thromboembolic risk with IVIg: Incidence and risk factors in patients with inflammatory neuropathy.
Neurology
; 94(6): e635-e638, 2020 02 11.
Article
em En
| MEDLINE
| ID: mdl-31852814
ABSTRACT
Our objective was to evaluate whether IV immunoglobulin (IVIg) increases the risk of thromboembolic events in neurology outpatients with inflammatory neuropathies, as there is conflicting evidence supporting this hypothesis, mainly from non-neurologic cohorts. We investigated this question over 30 months in our cohort of patients with inflammatory neuropathies receiving regular IVIg and found a greater incidence of arterial and venous thromboembolic events than population-based rates determined by hospital admissions data. Vascular risk factors were more common in the event group but there were no IVIg administration factors that contributed to the risk. This study suggests that IVIg may have a small but contributory role in determining thromboembolic risk in the inflammatory neuropathy cohort and more evidence is required before it is clear whether the current primary prevention guidelines are appropriate in this group of patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Polineuropatias
/
Tromboembolia
/
Imunoglobulinas Intravenosas
/
Polirradiculoneuropatia Desmielinizante Inflamatória Crônica
/
Fatores Imunológicos
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article