3D printing of fillable individual thyroid replicas based on nuclear medicine DICOM data used as phantoms for gamma probe calibration.
Nuklearmedizin
; 59(1): 12-19, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31856284
ABSTRACT
AIM:
To proof the feasibility of manufacturing patient-indivdual (anthropomorphic) thyroid replicas from I-124 PET DICOM datasets by means of 3D printing. A possible field of application is the use of those phantoms for the calibration of gamma probes.METHODS:
After editing of the DICOM datasets using several software types and transferring into a dedicated stereolithography format, 10 fillable thyroid replicas (35-200âmL) made of polylactide acid were manufactured via 3D printing. All replicas were filled with a water-solution containing 3.5âMBq I-131 and applied to a standard neck phantom. Calibration factor measurements were carried out using a clinical gamma probe. Measurements were performed with three different tilts +â15°, 0° and -15°. The influence of the replicas' volume and the tilt was investigated.RESULTS:
Manufacturing of the replicas was successful in all cases. The time required for data processing was 13â±â2 (median 12, range 9-25) min and 4-11âh for 3D printing (size-dependent). The printing process could be done overnight. Measured mean calibration factor for straight gamma probe positioning (0° tilt) was 31â965â±â3360 (33â893, 25â470-34â253) cpm/MBq. A tilt of -15° resulted in lower calibration factors (-7.7â%), whereas a tilt of +â15° led to higher values (+â9.5â%); pâ=â0.001. The calibration factors were highly inversely proportional correlated to the volume of the replicas (râ=â-0.91, pâ<â0.001).CONCLUSION:
3D printing of patient-individual (anthropomorphic) fillable thyroid replicas was feasable for a large range of volumes. The study demonstrates the influence of the volume as well as the tilt of the measured object for calibration factor measurements with gamma probes.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Glândula Tireoide
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Imagens de Fantasmas
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Tomografia por Emissão de Pósitrons
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Impressão Tridimensional
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Raios gama
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Medicina Nuclear
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article