[Clinical- epidemiological characteristics and predictors of coronary complications in children of Argentina with Kawasaki disease]. / Características clínico-epidemiológicas y predictores de complicaciones coronarias en niños de Argentina con enfermedad de Kawasaki.
Rev Chilena Infectol
; 36(5): 636-641, 2019 Oct.
Article
em Es
| MEDLINE
| ID: mdl-31859805
ABSTRACT
BACKGROUND:
Kawasaki disease (EK) is an acute systemic vasculitis with a risk of developing coronary aneurysms.AIM:
To describe the clinical and epidemiological characteristics of children with EK in Argentina and to analyse the risk factors for the development of coronary's complications (CC).METHODS:
Multicenter, retrospective, cross-sectional, observational and analytical study. It included patients younger than 18 years of age diagnosed with EK in hospitals in Argentina, between January the 1st, 2010 and December the 31th, 2013.RESULTS:
N = 193 subjects. Age medium 29 months. Total incidence 5 cases / 10,000 hospital discharges. CC was observed in 15.5% of patients. Increased risk factors for CC Elevated number of days with fever at the time of treatment placement (p = 0.0033); Increased of heart frequency (p = 0.0021), erythrosedimentation (ESR) (p = 0.005), C-reactive protein (CRP) (p < 0.0001), leukocytes (p = 0.0006), neutrophils (p = 0.0021); Decreased of hematocrit (p = 0.0007) and hemoglobin (p < 0.0001).Association with CC non-coronary cardiological alterations (OR = 10,818); PCR greater than 68 mg /L (OR = 11,596); leukocytes greater than 20,000 / mm3 (OR = 4.316); and ESR greater than 64 mm / 1 hour (OR = 4.267).CONCLUSION:
The most frequent form of presentation was complete EK, the risk of CC was higher in males, younger than 5 years old, the risk factors (clinical and laboratory) were similar to those described in the literature.
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Base de dados:
MEDLINE
Assunto principal:
Doença das Coronárias
/
Síndrome de Linfonodos Mucocutâneos
Idioma:
Es
Ano de publicação:
2019
Tipo de documento:
Article