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Local delivery of corticosteroids in clinical ophthalmology: A review.
Fung, Adrian T; Tran, Tuan; Lim, Lyndell L; Samarawickrama, Chameen; Arnold, Jennifer; Gillies, Mark; Catt, Caroline; Mitchell, Logan; Symons, Andrew; Buttery, Robert; Cottee, Lisa; Tumuluri, Krishna; Beaumont, Paul.
Afiliação
  • Fung AT; Westmead Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
  • Tran T; Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.
  • Lim LL; Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
  • Samarawickrama C; Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
  • Arnold J; Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.
  • Gillies M; Centre for Eye Research Australia, Melbourne, Victoria, Australia.
  • Catt C; University of Melbourne, Melbourne, Victoria, Australia.
  • Mitchell L; Westmead Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
  • Symons A; Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
  • Buttery R; Liverpool Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
  • Cottee L; Marsden Eye Specialists, Sydney, New South Wales, Australia.
  • Tumuluri K; Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
  • Beaumont P; Save Sight Institute, Central Clinical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, New South Wales, Australia.
Clin Exp Ophthalmol ; 48(3): 366-401, 2020 04.
Article em En | MEDLINE | ID: mdl-31860766
ABSTRACT
Locally administered steroids have a long history in ophthalmology for the treatment of inflammatory conditions. Anterior segment conditions tend to be treated with topical steroids whilst posterior segment conditions generally require periocular, intravitreal or systemic administration for penetration. Over recent decades, the clinical applications of periocular steroid delivery have expanded to a wide range of conditions including macular oedema from retino-vascular conditions. Formulations have been developed with the aim to provide practical, targeted, longer-term and more efficacious therapy whilst minimizing side effects. Herein, we provide a comprehensive overview of the types of periocular steroid delivery, their clinical applications in ophthalmology and their side effects.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oftalmologia / Edema Macular / Glucocorticoides Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oftalmologia / Edema Macular / Glucocorticoides Idioma: En Ano de publicação: 2020 Tipo de documento: Article