DNA Modification Readers and Writers and Their Interplay.
J Mol Biol
; 432(6): 1731-1746, 2020 Mar 13.
Article
em En
| MEDLINE
| ID: mdl-31866298
Genomic DNA is modified in a postreplicative manner and several modifications, the enzymes responsible for their deposition as well as proteins that read these modifications, have been described. Here, we focus on the impact of DNA modifications on the DNA helix and review the writers and readers of cytosine modifications and how they interplay to shape genome composition, stability, and function.
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MEDLINE
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En
Ano de publicação:
2020
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Article