Discovery of WS-157 as a highly potent, selective and orally active EGFR inhibitor.

He, Pengxing; Niu, Shenghui; Wang, Shuai; Shi, Xiaojing; Feng, Siqi; Du, Linna; Zhang, Xuyang; Ma, Zhilu; Yu, Bin; Liu, Hongmin.

Afiliação

He P; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Niu S; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Wang S; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Shi X; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Feng S; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Du L; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhang X; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Ma Z; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Yu B; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Liu H; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China.