Structurally Diverse Meroterpenoids from a Marine-Derived Aspergillus sp. Fungus.
J Nat Prod
; 83(1): 99-104, 2020 01 24.
Article
em En
| MEDLINE
| ID: mdl-31867967
ABSTRACT
Three new meroterpenoids, asperaustins A-C (1-3), and seven known analogues (4-10) were isolated from a marine-derived Aspergillus sp. fungus. The structures and absolute configurations of these new compounds were unequivocally determined by extensive spectroscopic analyses and single-crystal X-ray diffraction analyses. Asperaustin A (1) possesses an unusual spiro[4.5]deca-3,6-dien-2-one moiety with a unique 5/6/6/6/5 pentacyclic skeleton. The absolute configurations of austinoneol A (7) and precalidodehydroaustin (9) were determined by single-crystal X-ray diffraction analyses using Cu Kα radiation for the first time.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aspergillus
/
Terpenos
/
Fungos
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article