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Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors.
Laghezza, Antonio; Luisi, Grazia; Caradonna, Alessia; Di Pizio, Antonella; Piemontese, Luca; Loiodice, Fulvio; Agamennone, Mariangela; Tortorella, Paolo.
Afiliação
  • Laghezza A; Department of Pharmacy and Pharmaceutical Sciences, "A. Moro" University of Bari, Bari, Italy.
  • Luisi G; Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
  • Caradonna A; Department of Pharmacy and Pharmaceutical Sciences, "A. Moro" University of Bari, Bari, Italy.
  • Di Pizio A; Section In Silico Biology & Machine Learning, Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.
  • Piemontese L; Department of Pharmacy and Pharmaceutical Sciences, "A. Moro" University of Bari, Bari, Italy.
  • Loiodice F; Department of Pharmacy and Pharmaceutical Sciences, "A. Moro" University of Bari, Bari, Italy.
  • Agamennone M; Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy. Electronic address: m.agamennone@unich.it.
  • Tortorella P; Department of Pharmacy and Pharmaceutical Sciences, "A. Moro" University of Bari, Bari, Italy. Electronic address: paolo.tortorella@uniba.it.
Bioorg Med Chem ; 28(3): 115257, 2020 02 01.
Article em En | MEDLINE | ID: mdl-31874775
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / Metaloproteinase 2 da Matriz / Inibidores de Metaloproteinases de Matriz Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / Metaloproteinase 2 da Matriz / Inibidores de Metaloproteinases de Matriz Idioma: En Ano de publicação: 2020 Tipo de documento: Article