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Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance.
McNeil, Helen E; Alav, Ilyas; Torres, Ricardo Corona; Rossiter, Amanda E; Laycock, Eve; Legood, Simon; Kaur, Inderpreet; Davies, Matthew; Wand, Matthew; Webber, Mark A; Bavro, Vassiliy N; Blair, Jessica M A.
Afiliação
  • McNeil HE; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Alav I; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Torres RC; School of Life Sciences, University of Essex, Colchester, United Kingdom.
  • Rossiter AE; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Laycock E; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Legood S; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Kaur I; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Davies M; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
  • Wand M; Public Health England, National Infection Service, Porton Down, Salisbury, Wiltshire, United Kingdom.
  • Webber MA; Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.
  • Bavro VN; School of Life Sciences, University of Essex, Colchester, United Kingdom.
  • Blair JMA; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
PLoS Pathog ; 15(12): e1008101, 2019 12.
Article em En | MEDLINE | ID: mdl-31877175
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Farmacorresistência Bacteriana / Antibacterianos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Farmacorresistência Bacteriana / Antibacterianos Idioma: En Ano de publicação: 2019 Tipo de documento: Article