Autophagy Induction by HDAC Inhibitors Is Unlikely to be the Mechanism of Efficacy in Prevention of Retinal Degeneration Caused by P23H Rhodopsin.

Wen, Runxia H; Loewen, Aaron D; Vent-Schmidt, Ruanne Y J; Moritz, Orson L

Autophagy Induction by HDAC Inhibitors Is Unlikely to be the Mechanism of Efficacy in Prevention of Retinal Degeneration Caused by P23H Rhodopsin.

Wen, Runxia H; Loewen, Aaron D; Vent-Schmidt, Ruanne Y J; Moritz, Orson L.

Afiliação

Wen RH; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
Loewen AD; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
Vent-Schmidt RYJ; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
Moritz OL; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada. olmoritz@mail.ubc.ca.

Adv Exp Med Biol ; 1185: 401-405, 2019.

Article em En | MEDLINE | ID: mdl-31884645

Assuntos

Autofagia; Inibidores de Histona Desacetilases/farmacologia; Degeneração Retiniana/prevenção & controle; Rodopsina/efeitos adversos; Animais; Modelos Animais de Doenças; Larva; Degeneração Retiniana/induzido quimicamente; Xenopus laevis

Palavras-chave

Autophagy; Chloroquine; Histone deacetylase inhibitor; Rapamycin; Retinitis pigmentosa; Transgenic Xenopus laevis; Valproic acid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Degeneração Retiniana / Rodopsina / Autofagia / Inibidores de Histona Desacetilases Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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