Sodium-hydrogen exchanger regulatory factor-1 (NHERF1) confers salt sensitivity in both male and female models of hypertension in aging.

Pushpakumar, Sathnur; Ahmad, Asrar; Ketchem, Corey J; Jose, Pedro A; Weinman, Edward J; Sen, Utpal; Lederer, Eleanor D; Khundmiri, Syed J

Pushpakumar, Sathnur; Ahmad, Asrar; Ketchem, Corey J; Jose, Pedro A; Weinman, Edward J; Sen, Utpal; Lederer, Eleanor D; Khundmiri, Syed J.

Afiliação

Pushpakumar S; Department of Physiology, University of Louisville, Louisville, KY, United States of America.
Ahmad A; Department of Physiology and Biophysics, Howard University College of Medicine, Washington, DC, United States of America.
Ketchem CJ; Department of Medicine, Nephrology and Hypertension, University of Louisville, Louisville, KY, United States of America.
Jose PA; Department of Medicine, Division of Renal Diseases and Hypertension, The George Washington University, Washington, DC, United States of America.
Weinman EJ; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States of America.
Sen U; Department of Physiology, University of Louisville, Louisville, KY, United States of America.
Lederer ED; Department of Physiology, University of Louisville, Louisville, KY, United States of America; Department of Medicine, Nephrology and Hypertension, University of Louisville, Louisville, KY, United States of America; Robley Rex VA Medical Center, Louisville, KY, United States of America.
Khundmiri SJ; Department of Physiology and Biophysics, Howard University College of Medicine, Washington, DC, United States of America. Electronic address: syed.khundmiri@howard.edu.

Life Sci ; 243: 117226, 2020 Feb 15.

Article em En | MEDLINE | ID: mdl-31904366

Assuntos

Envelhecimento/metabolismo; Hipertensão/metabolismo; Fosfoproteínas/fisiologia; Cloreto de Sódio na Dieta/administração & dosagem; Trocadores de Sódio-Hidrogênio/fisiologia; Animais; Pressão Sanguínea; Modelos Animais de Doenças; Feminino; Rim/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fosfoproteínas/genética; Ratos; Ratos Endogâmicos F344; Trocadores de Sódio-Hidrogênio/genética

Palavras-chave

Aging; Kidney; NHERF1; Salt sensitive hypertension; Transporters

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Envelhecimento / Trocadores de Sódio-Hidrogênio / Cloreto de Sódio na Dieta / Hipertensão Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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