Remote Electrical Neuromodulation (REN) for the Acute Treatment of Migraine.
Headache
; 60(1): 229-234, 2020 01.
Article
em En
| MEDLINE
| ID: mdl-31913517
ABSTRACT
There is a significant unmet need for novel, effective, and well-tolerated acute migraine treatments. Remote electrical neuromodulation (REN) is a non-pharmacological, non-invasive, acute migraine treatment that stimulates upper arm peripheral nerves to induce conditioned pain modulation - an endogenous analgesic mechanism in which a conditioning stimulation inhibits pain in remote body regions. This review presents the method of action and the clinical data of REN and discusses its potential patient benefits. The clinically meaningful efficacy, together with a very favorable safety profile, suggests that REN may offer a promising alternative for the acute treatment of migraine and could be considered first-line treatment in some patients.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Terapia por Estimulação Elétrica
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Analgesia
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Nervo Mediano
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Transtornos de Enxaqueca
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Nervo Musculocutâneo
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article