Conditional knockout of kisspeptin signaling in brown adipose tissue increases metabolic rate and body temperature and lowers body weight.

Tolson, Kristen P; Marooki, Nuha; De Bond, Julie-Ann P; Walenta, Evelyn; Stephens, Shannon B Z; Liaw, Reanna B; Savur, Rishi; Wolfe, Andrew; Oh, Da Young; Smith, Jeremy T; Kauffman, Alexander S

Tolson, Kristen P; Marooki, Nuha; De Bond, Julie-Ann P; Walenta, Evelyn; Stephens, Shannon B Z; Liaw, Reanna B; Savur, Rishi; Wolfe, Andrew; Oh, Da Young; Smith, Jeremy T; Kauffman, Alexander S.

Afiliação

Tolson KP; Department of OBGYN and Reproductive Sciences, University of California, San Diego, CA, USA.
Marooki N; Department of OBGYN and Reproductive Sciences, University of California, San Diego, CA, USA.
De Bond JP; School of Human Sciences, University of Western Australia, Perth, WA, Australia.
Walenta E; Department of Medicine, University of California, San Diego, CA, USA.
Stephens SBZ; Department of OBGYN and Reproductive Sciences, University of California, San Diego, CA, USA.
Liaw RB; Department of OBGYN and Reproductive Sciences, University of California, San Diego, CA, USA.
Savur R; Department of OBGYN and Reproductive Sciences, University of California, San Diego, CA, USA.
Wolfe A; Department of Pediatrics and Physiology, Johns Hopkins University, Baltimore, MD, USA.
Oh DY; Department of Medicine, University of California, San Diego, CA, USA.
Smith JT; School of Human Sciences, University of Western Australia, Perth, WA, Australia.
Kauffman AS; Department of OBGYN and Reproductive Sciences, University of California, San Diego, CA, USA.

FASEB J ; 34(1): 107-121, 2020 01.

Article em En | MEDLINE | ID: mdl-31914628

Assuntos

Adipócitos Marrons/metabolismo; Temperatura Corporal/fisiologia; Peso Corporal/fisiologia; Metabolismo Energético/genética; Metabolismo Energético/fisiologia; Receptores de Kisspeptina-1/metabolismo; Animais; Temperatura Corporal/genética; Peso Corporal/genética; Genótipo; Camundongos; Camundongos Knockout; Receptores de Kisspeptina-1/genética

Palavras-chave

BAT; GPR54; Kiss1; Kiss1r; adipose; fat; kisspeptin; metabolism; obesity; temperature

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Temperatura Corporal / Peso Corporal / Metabolismo Energético / Adipócitos Marrons / Receptores de Kisspeptina-1 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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