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The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome.
Zhang, Mei-Juan; Zhao, Qiu-Chen; Xia, Ming-Xu; Chen, Jian; Chen, Yan-Ting; Cao, Xiang; Liu, Yi; Yuan, Zeng-Qiang; Wang, Xiao-Ying; Xu, Yun.
Afiliação
  • Zhang MJ; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Zhao QC; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Xia MX; Departments of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Chen J; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Chen YT; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Cao X; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Liu Y; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Yuan ZQ; Department of Neurology, Drum Tower Hospital, Medical School and The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China.
  • Wang XY; Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing, China.
  • Xu Y; Departments of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
FASEB J ; 34(1): 648-662, 2020 01.
Article em En | MEDLINE | ID: mdl-31914678
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilenodiaminas / Acrilamidas / Isquemia Encefálica / Proteínas de Ligação a DNA / Inibidores de Histona Desacetilases / Inflamassomos / Histona Desacetilases Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilenodiaminas / Acrilamidas / Isquemia Encefálica / Proteínas de Ligação a DNA / Inibidores de Histona Desacetilases / Inflamassomos / Histona Desacetilases Idioma: En Ano de publicação: 2020 Tipo de documento: Article