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PEGylated leuprolide with improved pharmacokinetic properties.
Fu, Mian; Zhuang, Xiaomei; Zhang, Tianhong; Guan, Ying; Meng, Qingbin; Zhang, Yongjun.
Afiliação
  • Fu M; Key Laboratory of Functional Polymer Materials and State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China.
  • Zhuang X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, 27 Taiping Road, Beijing 100850, China.
  • Zhang T; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, 27 Taiping Road, Beijing 100850, China.
  • Guan Y; Key Laboratory of Functional Polymer Materials and State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China. Electronic address: yingguan@nankai.edu.cn.
  • Meng Q; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, 27 Taiping Road, Beijing 100850, China. Electronic address: nankaimqb@sina.com.
  • Zhang Y; Key Laboratory of Functional Polymer Materials and State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China. Electronic address: yongjunzhang@nankai.edu.cn.
Bioorg Med Chem ; 28(4): 115306, 2020 02 15.
Article em En | MEDLINE | ID: mdl-31926774
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leuprolida Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leuprolida Idioma: En Ano de publicação: 2020 Tipo de documento: Article