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Structure-Specific Cleavage of an RNA Repeat Expansion with a Dimeric Small Molecule Is Advantageous over Sequence-Specific Recognition by an Oligonucleotide.
Benhamou, Raphael I; Angelbello, Alicia J; Andrews, Ryan J; Wang, Eric T; Moss, Walter N; Disney, Matthew D.
Afiliação
  • Benhamou RI; Department of Chemistry , The Scripps Research Institute , 110 Scripps Way , Jupiter , Florida 33458 , United States.
  • Angelbello AJ; Department of Chemistry , The Scripps Research Institute , 110 Scripps Way , Jupiter , Florida 33458 , United States.
  • Andrews RJ; Roy J. Carver Department of Biophysics, Biochemistry, and Molecular Biology , Iowa State University , Ames , Iowa 50011 , United States.
  • Wang ET; Department of Molecular Genetics and Microbiology, Center for NeuroGenetics, UF Genetics Institute , University of Florida , 2033 Mowry Road , Gainesville , Florida 32610 , United States.
  • Moss WN; Roy J. Carver Department of Biophysics, Biochemistry, and Molecular Biology , Iowa State University , Ames , Iowa 50011 , United States.
  • Disney MD; Department of Chemistry , The Scripps Research Institute , 110 Scripps Way , Jupiter , Florida 33458 , United States.
ACS Chem Biol ; 15(2): 485-493, 2020 02 21.
Article em En | MEDLINE | ID: mdl-31927948
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bleomicina / RNA / Sequências Repetitivas de Ácido Nucleico / Proteínas de Ligação a RNA / Clivagem do RNA Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bleomicina / RNA / Sequências Repetitivas de Ácido Nucleico / Proteínas de Ligação a RNA / Clivagem do RNA Idioma: En Ano de publicação: 2020 Tipo de documento: Article