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Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.
Lynn, Geoffrey M; Sedlik, Christine; Baharom, Faezzah; Zhu, Yaling; Ramirez-Valdez, Ramiro A; Coble, Vincent L; Tobin, Kennedy; Nichols, Sarah R; Itzkowitz, Yaakov; Zaidi, Neeha; Gammon, Joshua M; Blobel, Nicolas J; Denizeau, Jordan; de la Rochere, Philippe; Francica, Brian J; Decker, Brennan; Maciejewski, Mateusz; Cheung, Justin; Yamane, Hidehiro; Smelkinson, Margery G; Francica, Joseph R; Laga, Richard; Bernstock, Joshua D; Seymour, Leonard W; Drake, Charles G; Jewell, Christopher M; Lantz, Olivier; Piaggio, Eliane; Ishizuka, Andrew S; Seder, Robert A.
Afiliação
  • Lynn GM; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. geoffrey.lynn@avideatechnologies.com.
  • Sedlik C; Avidea Technologies, Inc, Baltimore, MD, USA. geoffrey.lynn@avideatechnologies.com.
  • Baharom F; Institut Curie, PSL Research University, Paris, France.
  • Zhu Y; Centre d'Investigation Clinique Biothérapie, Institut Curie, Paris, France.
  • Ramirez-Valdez RA; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Coble VL; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Tobin K; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Nichols SR; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Itzkowitz Y; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Zaidi N; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Gammon JM; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Blobel NJ; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Denizeau J; Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
  • de la Rochere P; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Francica BJ; Institut Curie, PSL Research University, Paris, France.
  • Decker B; Centre d'Investigation Clinique Biothérapie, Institut Curie, Paris, France.
  • Maciejewski M; Institut Curie, PSL Research University, Paris, France.
  • Cheung J; Centre d'Investigation Clinique Biothérapie, Institut Curie, Paris, France.
  • Yamane H; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
  • Smelkinson MG; Tempest Therapeutics, San Francisco, CA, USA.
  • Francica JR; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Laga R; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Bernstock JD; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Seymour LW; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Drake CG; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.
  • Jewell CM; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Lantz O; Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Piaggio E; Avidea Technologies, Inc, Baltimore, MD, USA.
  • Ishizuka AS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
  • Seder RA; Department of Oncology, University of Oxford, Oxford, UK.
Nat Biotechnol ; 38(3): 320-332, 2020 03.
Article em En | MEDLINE | ID: mdl-31932728
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Melanoma Experimental / Adjuvantes Imunológicos / Linfócitos T CD8-Positivos / Vacinas Anticâncer / Antígenos de Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Melanoma Experimental / Adjuvantes Imunológicos / Linfócitos T CD8-Positivos / Vacinas Anticâncer / Antígenos de Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article