DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing.

Zhou, Zilu; Xu, Bihui; Minn, Andy; Zhang, Nancy R

Zhou, Zilu; Xu, Bihui; Minn, Andy; Zhang, Nancy R.

Afiliação

Zhou Z; Graduate Group in Genomics and Computational Biology, University of Pennsylvania, Philadelphia, PA, USA.
Xu B; Department of Statistics, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA.
Minn A; Department of Radiation Oncology, Parker Institute for Cancer Immunotherapy, Abramson Family Cancer Research Institute, Graduate Group in Cell and Molecular Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhang NR; Department of Radiation Oncology, Parker Institute for Cancer Immunotherapy, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Genome Biol ; 21(1): 10, 2020 01 14.

Article em En | MEDLINE | ID: mdl-31937348

Assuntos

Heterogeneidade Genética; Técnicas Genéticas; Neoplasias/genética; Filogenia; Software; Animais; Humanos; Camundongos; Análise de Célula Única

Palavras-chave

Cancer genomics; Intratumor heterogeneity; Multi-omics analysis; Phylogeny inference; Single-cell RNA sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Filogenia / Software / Técnicas Genéticas / Heterogeneidade Genética / Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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