Tuna Bone Powder Alleviates Glucocorticoid-Induced Osteoporosis via Coregulation of the NF-&#954;B and Wnt/ß-Catenin Signaling Pathways and Modulation of Gut Microbiota Composition and Metabolism.

Li, Jingjing; Yang, Mingyuan; Lu, Chenyang; Han, Jiaojiao; Tang, Shasha; Zhou, Jun; Li, Ye; Ming, Tinghong; Wang, Zaijie Jim; Su, Xiurong

Tuna Bone Powder Alleviates Glucocorticoid-Induced Osteoporosis via Coregulation of the NF-κB and Wnt/ß-Catenin Signaling Pathways and Modulation of Gut Microbiota Composition and Metabolism.

Li, Jingjing; Yang, Mingyuan; Lu, Chenyang; Han, Jiaojiao; Tang, Shasha; Zhou, Jun; Li, Ye; Ming, Tinghong; Wang, Zaijie Jim; Su, Xiurong.

Afiliação

Li J; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315000, China.
Yang M; School of Marine Science, Ningbo University, Ningbo, 315000, China.
Lu C; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315000, China.
Han J; School of Marine Science, Ningbo University, Ningbo, 315000, China.
Tang S; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315000, China.
Zhou J; School of Marine Science, Ningbo University, Ningbo, 315000, China.
Li Y; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315000, China.
Ming T; School of Marine Science, Ningbo University, Ningbo, 315000, China.
Wang ZJ; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315000, China.
Su X; School of Marine Science, Ningbo University, Ningbo, 315000, China.

Mol Nutr Food Res ; 64(5): e1900861, 2020 03.

Article em En | MEDLINE | ID: mdl-31953894

Assuntos

Osso e Ossos/química; Microbioma Gastrointestinal/efeitos dos fármacos; Osteoporose/dietoterapia; Atum; Animais; Densidade Óssea/efeitos dos fármacos; Reabsorção Óssea/dietoterapia; Reabsorção Óssea/metabolismo; Ácidos Graxos Voláteis/metabolismo; Fezes; Feminino; Microbioma Gastrointestinal/fisiologia; Glucocorticoides/toxicidade; Inflamação/dietoterapia; Camundongos Endogâmicos ICR; NF-kappa B/metabolismo; Osteogênese/efeitos dos fármacos; Osteogênese/fisiologia; Osteoporose/induzido quimicamente; Osteoporose/metabolismo; Pós; Via de Sinalização Wnt/efeitos dos fármacos; beta Catenina/metabolismo

Palavras-chave

glucocorticoid-induced osteoporosis; gut microbiota; short-chain fatty acids; signaling pathways; tuna bone powder

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoporose / Atum / Osso e Ossos / Microbioma Gastrointestinal Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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