MLH1-mediated recruitment of FAN1 to chromatin for the induction of apoptosis triggered by O<sup>6</sup> -methylguanine.

Rikitake, Mihoko; Fujikane, Ryosuke; Obayashi, Yuko; Oka, Kyoko; Ozaki, Masao; Hidaka, Masumi

MLH1-mediated recruitment of FAN1 to chromatin for the induction of apoptosis triggered by O⁶ -methylguanine.

Rikitake, Mihoko; Fujikane, Ryosuke; Obayashi, Yuko; Oka, Kyoko; Ozaki, Masao; Hidaka, Masumi.

Afiliação

Rikitake M; Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan.
Fujikane R; Department of Oral Growth and Development, Fukuoka Dental College, Fukuoka, Japan.
Obayashi Y; Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan.
Oka K; Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan.
Ozaki M; Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan.
Hidaka M; Department of Oral and Maxillofacial Surgery, Fukuoka Dental College, Fukuoka, Japan.

Genes Cells ; 25(3): 175-186, 2020 Mar.

Article em En | MEDLINE | ID: mdl-31955481

Assuntos

Apoptose/efeitos dos fármacos; Cromatina/metabolismo; Endodesoxirribonucleases/metabolismo; Exodesoxirribonucleases/metabolismo; Guanina/análogos & derivados; Enzimas Multifuncionais/metabolismo; Proteína 1 Homóloga a MutL/metabolismo; Dano ao DNA; Endodesoxirribonucleases/genética; Exodesoxirribonucleases/genética; Guanina/farmacologia; Células HeLa; Humanos; Enzimas Multifuncionais/genética

Palavras-chave

FANCD2 and FANCI-associated nuclease 1 (FAN1); MLH1; O6-methylguanine; apoptosis; mismatch repair (MMR)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Apoptose / Endodesoxirribonucleases / Exodesoxirribonucleases / Enzimas Multifuncionais / Proteína 1 Homóloga a MutL / Guanina Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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