Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.

Georgakis, Marios K; Malik, Rainer; Anderson, Christopher D; Parhofer, Klaus G; Hopewell, Jemma C; Dichgans, Martin

Georgakis, Marios K; Malik, Rainer; Anderson, Christopher D; Parhofer, Klaus G; Hopewell, Jemma C; Dichgans, Martin.

Afiliação

Georgakis MK; Institute for Stroke and Dementia Research (ISD), University Hospital of Ludwig-Maximilians-University (LMU), Munich, Germany.
Malik R; Graduate School for Systemic Neurosciences (GSN), Ludwig-Maximilians-University (LMU), Munich, Germany.
Anderson CD; Institute for Stroke and Dementia Research (ISD), University Hospital of Ludwig-Maximilians-University (LMU), Munich, Germany.
Parhofer KG; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Hopewell JC; Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Dichgans M; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.

Brain ; 143(2): 597-610, 2020 02 01.

Article em En | MEDLINE | ID: mdl-31968102

Assuntos

Doenças de Pequenos Vasos Cerebrais/genética; HDL-Colesterol/genética; LDL-Colesterol/genética; Colesterol/sangue; Lipídeos/sangue; HDL-Colesterol/sangue; LDL-Colesterol/sangue; Predisposição Genética para Doença/genética; Estudo de Associação Genômica Ampla; Humanos; Fatores de Risco; Triglicerídeos/sangue; Triglicerídeos/genética

Palavras-chave

Mendelian randomization; high-density lipoprotein; lacunar stroke; lipids; small vessel disease

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Doenças de Pequenos Vasos Cerebrais / Lipídeos / HDL-Colesterol / LDL-Colesterol Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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