Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data.

Lenk, Lennart; Alsadeq, Ameera; Schewe, Denis M

Lenk, Lennart; Alsadeq, Ameera; Schewe, Denis M.

Afiliação

Lenk L; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
Alsadeq A; Institute of Immunology, Ulm University Medical Center, Ulm, Germany.
Schewe DM; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. denis.schewe@uksh.de.

Cancer Metastasis Rev ; 39(1): 173-187, 2020 03.

Article em En | MEDLINE | ID: mdl-31970588

Assuntos

Sistema Nervoso Central/patologia; Infiltração Leucêmica/patologia; Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia; Criança; Humanos

Palavras-chave

Acute lymphoblastic leukemia; Blood-brain-barrier; CNS involvement; Central nervous system; Immunotherapy; Tumor dormancy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Infiltração Leucêmica / Leucemia-Linfoma Linfoblástico de Células Precursoras Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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