Are the current gRNA ranking prediction algorithms useful for genome editing in plants?

Naim, Fatima; Shand, Kylie; Hayashi, Satomi; O'Brien, Martin; McGree, James; Johnson, Alexander A T; Dugdale, Benjamin; Waterhouse, Peter M

Naim, Fatima; Shand, Kylie; Hayashi, Satomi; O'Brien, Martin; McGree, James; Johnson, Alexander A T; Dugdale, Benjamin; Waterhouse, Peter M.

Afiliação

Naim F; Centre for Tropical Crops and Biocommodities, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland, Australia.
Shand K; Centre for Crop and Disease Management, School of Molecular and Life Sciences, Curtin University, Bentley, Western Australia, Australia.
Hayashi S; Centre for Tropical Crops and Biocommodities, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland, Australia.
O'Brien M; Centre for Tropical Crops and Biocommodities, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland, Australia.
McGree J; School of BioSciences, The University of Melbourne, Melbourne, Victoria, Australia.
Johnson AAT; School of Mathematical Sciences, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland, Australia.
Dugdale B; School of BioSciences, The University of Melbourne, Melbourne, Victoria, Australia.
Waterhouse PM; Centre for Tropical Crops and Biocommodities, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland, Australia.

PLoS One ; 15(1): e0227994, 2020.

Article em En | MEDLINE | ID: mdl-31978124

Assuntos

Algoritmos; Edição de Genes; Genoma de Planta; Plantas/genética; RNA Guia de Cinetoplastídeos/genética; Sequência de Bases; Proteína 9 Associada à CRISPR/metabolismo; Folhas de Planta/genética; Plantas Geneticamente Modificadas; Nicotiana/genética; Transgenes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plantas / Algoritmos / RNA Guia de Cinetoplastídeos / Genoma de Planta / Edição de Genes Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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