Knockdown of MALAT1 attenuates high-glucose-induced angiogenesis and inflammation via endoplasmic reticulum stress in human retinal vascular endothelial cells.

Wang, Yuan; Wang, Ling; Guo, Hui; Peng, Yun; Nie, Danyao; Mo, Jinsong; Ye, Lin

Wang, Yuan; Wang, Ling; Guo, Hui; Peng, Yun; Nie, Danyao; Mo, Jinsong; Ye, Lin.

Afiliação

Wang Y; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi
Wang L; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi
Guo H; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi
Peng Y; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi
Nie D; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi
Mo J; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi
Ye L; Shenzhen Eye Hospital, Shenzhen 518040, Guangdong, China; Visual·Optic Institute, Health Science Center, Shenzhen University, Shenzhen·518037, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen 518040, Chi

Biomed Pharmacother ; 124: 109699, 2020 Apr.

Article em En | MEDLINE | ID: mdl-31986419

Assuntos

Retinopatia Diabética/genética; Estresse do Retículo Endoplasmático/genética; RNA Longo não Codificante/genética; Neovascularização Retiniana/genética; Proliferação de Células/genética; Sobrevivência Celular/genética; Células Cultivadas; Citocinas/metabolismo; Retinopatia Diabética/patologia; Chaperona BiP do Retículo Endoplasmático; Células Endoteliais/patologia; Técnicas de Silenciamento de Genes; Glucose; Humanos; Inflamação/genética; Inflamação/patologia; Retina/citologia; Retina/patologia; Neovascularização Retiniana/patologia

Palavras-chave

Diabetic retinopathy; GRP78; MALAT1; Retinal vascular endothelial cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização Retiniana / Retinopatia Diabética / Estresse do Retículo Endoplasmático / RNA Longo não Codificante Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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