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Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.
Tang, Juan; Tu, Sha; Lin, Guoxin; Guo, Hui; Yan, Chengkai; Liu, Qingjun; Huang, Ling; Tang, Na; Xiao, Yizhi; Pope, R Marshall; Rajaram, Murugesan V S; Amer, Amal O; Ahmer, Brian M; Gunn, John S; Wozniak, Daniel J; Tao, Lijian; Coppola, Vincenzo; Zhang, Liwen; Langdon, Wallace Y; Torrelles, Jordi B; Lipkowitz, Stanley; Zhang, Jian.
Afiliação
  • Tang J; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Tu S; Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
  • Lin G; Department of Pathology, University of Iowa, Iowa City, IA.
  • Guo H; Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
  • Yan C; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Liu Q; Department of Pathology, University of Iowa, Iowa City, IA.
  • Huang L; Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
  • Tang N; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Xiao Y; Department of Pathology, University of Iowa, Iowa City, IA.
  • Pope RM; Department of Pathology, University of Iowa, Iowa City, IA.
  • Rajaram MVS; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Amer AO; Department of Pathology, University of Iowa, Iowa City, IA.
  • Ahmer BM; Department of Pathology, University of Iowa, Iowa City, IA.
  • Gunn JS; Department of Pathology, University of Iowa, Iowa City, IA.
  • Wozniak DJ; Proteomics Facility, University of Iowa Carver College of Medicine, Iowa City, IA.
  • Tao L; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Coppola V; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Zhang L; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Langdon WY; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Torrelles JB; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH.
  • Lipkowitz S; Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
  • Zhang J; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH.
J Exp Med ; 217(4)2020 04 06.
Article em En | MEDLINE | ID: mdl-31999304
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotoxemia / Ubiquitina-Proteína Ligases / Proteínas Adaptadoras de Transdução de Sinal / Proteínas Proto-Oncogênicas c-cbl / Ubiquitinação / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotoxemia / Ubiquitina-Proteína Ligases / Proteínas Adaptadoras de Transdução de Sinal / Proteínas Proto-Oncogênicas c-cbl / Ubiquitinação / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Ano de publicação: 2020 Tipo de documento: Article