Doxorubicin-Loaded Carbon Dots Lipid-Coated Calcium Phosphate Nanoparticles for Visual Targeted Delivery and Therapy of Tumor.

Zhang, Jian; Zhang, Hongyan; Jiang, Jianqi; Cui, Nan; Xue, Xiao; Wang, Tianying; Wang, Xiaoqiang; He, Yunpeng; Wang, Dongkai

Zhang, Jian; Zhang, Hongyan; Jiang, Jianqi; Cui, Nan; Xue, Xiao; Wang, Tianying; Wang, Xiaoqiang; He, Yunpeng; Wang, Dongkai.

Afiliação

Zhang J; Department of Chinese Medicine Pharmacology, School of Traditional Chinese Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Zhang H; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Jiang J; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Cui N; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Xue X; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Wang T; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Wang X; Department of Pharmaceutical Chemistry, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
He Y; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Wang D; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.

Int J Nanomedicine ; 15: 433-444, 2020.

Article em En | MEDLINE | ID: mdl-32021189

Assuntos

Antibióticos Antineoplásicos/administração & dosagem; Fosfatos de Cálcio/química; Doxorrubicina/administração & dosagem; Sistemas de Liberação de Medicamentos/métodos; Nanopartículas/química; Animais; Antibióticos Antineoplásicos/farmacocinética; Antibióticos Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Carbono/química; Doxorrubicina/farmacocinética; Doxorrubicina/farmacologia; Liberação Controlada de Fármacos; Células Hep G2; Humanos; Concentração de Íons de Hidrogênio; Lipídeos/química; Masculino; Camundongos; Neoplasias Experimentais/diagnóstico por imagem; Distribuição Tecidual; Microambiente Tumoral/efeitos dos fármacos; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

bioimaging; calcium phosphate photodynamic therapy; carbon dots; pH-sensitive; therapy; tumor targeting

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatos de Cálcio / Doxorrubicina / Sistemas de Liberação de Medicamentos / Nanopartículas / Antibióticos Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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