Keeping Fibrotic Responses in Contractile Tissues at Bay: The Plot t(Hic1)ens.

Kim, Johnny; Braun, Thomas

Kim, Johnny; Braun, Thomas.

Afiliação

Kim J; Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany, The German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main.
Braun T; Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany, The German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main. Electronic address: thomas.braun@mpi-bn.mpg.de.

Cell Stem Cell ; 26(2): 129-130, 2020 02 06.

Article em En | MEDLINE | ID: mdl-32032520

ABSTRACT

ABSTRACT

Two recent papers in Cell Stem Cell by Soliman et al. (2020) and Scott et al. (2019) explore the contributions of mesenchymal progenitor cells to fibrosis in heart and skeletal muscle. They find tissue-dependent roles for a subpopulation of mesenchymal progenitors expressing Hic1 with varied differentiation capacities and pathophysiologic contributions.

Assuntos

Células-Tronco Mesenquimais; Diferenciação Celular; Divisão Celular; Fibrose; Humanos; Fatores de Transcrição Kruppel-Like; Músculo Esquelético

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Mesenquimais Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Mesenquimais Idioma: En Ano de publicação: 2020 Tipo de documento: Article