Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload.

Guo, Xinji; Kolpakov, Mikhail A; Hooshdaran, Bahman; Schappell, William; Wang, Tao; Eguchi, Satoru; Elliott, Katherine J; Tilley, Douglas G; Rao, A Koneti; Andrade-Gordon, Patricia; Bunce, Matthew; Madhu, Chintala; Houser, Steven R; Sabri, Abdelkarim.

Afiliação

Guo X; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Kolpakov MA; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Hooshdaran B; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Schappell W; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Wang T; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Eguchi S; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Elliott KJ; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Tilley DG; Center of Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Rao AK; Sol Sherry Thrombosis Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Andrade-Gordon P; Janssen Pharmaceutical, Spring House, Pennsylvania.
Bunce M; Janssen Pharmaceutical, Spring House, Pennsylvania.
Madhu C; Janssen Pharmaceutical, Spring House, Pennsylvania.
Houser SR; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Sabri A; Cardiovascular Research Center, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.

JACC Basic Transl Sci ; 5(1): 69-83, 2020 Jan.

Article em En | MEDLINE | ID: mdl-32043021

Palavras-chave

FXa, activated coagulation factor X; HF, heart failure; PAR, protease-activated receptor; PO, pressure-overload; PT, prothrombin time; TAC, transverse aortic constriction; aPTT, activated partial thromboplastin time; activated coagulation factor X; cardiac hypertrophy; coagulation; fibrosis; protease-activated receptors; rivaroxaban

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article