Bioadhesive supramolecular hydrogel from unprotected, short d,l-peptides with Phe-Phe and Leu-Asp-Val motifs.
Chem Commun (Camb)
; 56(20): 3015-3018, 2020 Mar 10.
Article
em En
| MEDLINE
| ID: mdl-32048648
ABSTRACT
The uncapped tripeptide DPhe-Phe-Leu acts as self-assembly template to yield supramolecular hydrogel biomaterials. As an example, self-assembling DPhe-Phe-Leu-Asp-Val contains the LDV bioadhesive motif for ß1 integrin activation. Hydrogels made of the two peptides successfully mimic fibronectin of the extracellular matrix and lead to high cell viability, adhesion, and spreading.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Hidrogéis
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Imagem Óptica
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article