Postconditioning Protection Against Myocardiocyte Anoxia/Reoxygenation Injury From Penehyclidine Hydrochloride.

Ren, J Y; Lin, D M; Wang, C B; Yang, Y L; Wang, Z Q; Cui, B Q; Ma, J

Ren, J Y; Lin, D M; Wang, C B; Yang, Y L; Wang, Z Q; Cui, B Q; Ma, J.

Afiliação

Ren JY; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.
Lin DM; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.
Wang CB; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.
Yang YL; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.
Wang ZQ; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.
Cui BQ; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.
Ma J; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.

Drug Des Devel Ther ; 13: 3977-3988, 2019.

Article em En | MEDLINE | ID: mdl-32063699

Assuntos

Hipóxia/tratamento farmacológico; Traumatismo por Reperfusão Miocárdica/tratamento farmacológico; Miócitos Cardíacos/efeitos dos fármacos; Substâncias Protetoras/farmacologia; Quinuclidinas/farmacologia; Apoptose/efeitos dos fármacos; Linhagem Celular; Humanos; Hipóxia/metabolismo; Hipóxia/patologia; Traumatismo por Reperfusão Miocárdica/metabolismo; Traumatismo por Reperfusão Miocárdica/patologia; Miócitos Cardíacos/metabolismo; Miócitos Cardíacos/patologia; Substâncias Protetoras/administração & dosagem; Quinuclidinas/administração & dosagem

Palavras-chave

A/R injury; PHC; anoxia/reoxygenation injury; cell apoptosis; mitochondrial pathway; oxidative stress; penehyclidine hydrochloride

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinuclidinas / Traumatismo por Reperfusão Miocárdica / Substâncias Protetoras / Miócitos Cardíacos / Hipóxia Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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