CELSR1 Promotes Neuroprotection in Cerebral Ischemic Injury Mainly Through the Wnt/PKC Signaling Pathway.

Wang, Li-Hong; Zhang, Geng-Lin; Liu, Xing-Yu; Peng, Ai; Ren, Hai-Yuan; Huang, Shu-Hong; Liu, Ting; Wang, Xiao-Jing

Wang, Li-Hong; Zhang, Geng-Lin; Liu, Xing-Yu; Peng, Ai; Ren, Hai-Yuan; Huang, Shu-Hong; Liu, Ting; Wang, Xiao-Jing.

Afiliação

Wang LH; Department of Cell Biology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China.
Zhang GL; Key Laboratory for Biotech-Drugs Ministry of Health and Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Shandong Medicinal Biotechnology Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250062, Shandong, China.
Liu XY; Department of Cell Biology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China.
Peng A; Department of Cell Biology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China.
Ren HY; Department of Cell Biology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China.
Huang SH; Institute of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250062, Shandong, China.
Liu T; Department of Cell Biology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China.
Wang XJ; Department of Cell Biology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China.

Int J Mol Sci ; 21(4)2020 Feb 13.

Article em En | MEDLINE | ID: mdl-32070035

Assuntos

Isquemia Encefálica/genética; Caderinas/genética; Neurogênese/genética; Acidente Vascular Cerebral/genética; Animais; Encéfalo/metabolismo; Encéfalo/patologia; Isquemia Encefálica/patologia; Proliferação de Células/genética; Modelos Animais de Doenças; Regulação da Expressão Gênica/genética; Hipocampo/metabolismo; Hipocampo/patologia; Humanos; Infarto da Artéria Cerebral Média/genética; Infarto da Artéria Cerebral Média/patologia; Ventrículos Laterais/metabolismo; Ventrículos Laterais/patologia; Células-Tronco Neurais/metabolismo; Células-Tronco Neurais/patologia; Fármacos Neuroprotetores/metabolismo; RNA Mensageiro/genética; Ratos; Acidente Vascular Cerebral/patologia; Via de Sinalização Wnt/genética

Palavras-chave

CELSR1; Wnt/PKC pathway; angiogenesis; neurogenesis; stroke

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caderinas / Isquemia Encefálica / Acidente Vascular Cerebral / Neurogênese Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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