Combined deep brain stimulation and thalamotomy for tremor-dominant Parkinson's disease.
J Clin Neurosci
; 74: 244-247, 2020 Apr.
Article
em En
| MEDLINE
| ID: mdl-32070669
ABSTRACT
Although deep brain stimulation (DBS) is an established treatment for Parkinson's disease, the long-term suppression of tremor is still a challenging issue. We report two patients with tremor-dominant Parkinson's disease (PD) treated with unilateral thalamotomy of the ventralis intermedius nucleus (Vim) combined with the subthalamic nucleus (STN)-DBS or the posterior subthalamic area (PSA)-DBS. One year after the surgery, thalamotomy of the area from the Vim to the PSA showed improvement not only in tremor but also in rigidity and akinesia. PSA- or STN-DBS with low intensity stimulation eliminated residual PD symptoms. Combined DBS and thalamotomy may provide long-term improvement of the majority of PD symptoms using lower therapeutic stimulation voltages.
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
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Tremor
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Núcleo Subtalâmico
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Núcleos Ventrais do Tálamo
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Estimulação Encefálica Profunda
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article