Establishment of optimal exercise therapy using near-infrared spectroscopy monitoring of tissue muscle oxygenation after therapeutic angiogenesis for patients with critical limb ischemia: A multicenter, randomized, controlled trial.

Shoji, Keisuke; Yanishi, Kenji; Shiraishi, Hirokazu; Yamabata, Shiho; Yukawa, Arito; Teramukai, Satoshi; Imai, Kojiro; Ito-Ihara, Toshiko; Tao, Masami; Higashi, Yukihito; Ishigami, Tomoaki; Fukumoto, Yoshihiro; Kuwahara, Koichiro; Matoba, Satoaki

Shoji, Keisuke; Yanishi, Kenji; Shiraishi, Hirokazu; Yamabata, Shiho; Yukawa, Arito; Teramukai, Satoshi; Imai, Kojiro; Ito-Ihara, Toshiko; Tao, Masami; Higashi, Yukihito; Ishigami, Tomoaki; Fukumoto, Yoshihiro; Kuwahara, Koichiro; Matoba, Satoaki.

Afiliação

Shoji K; Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yanishi K; Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Shiraishi H; Rehabilitation Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yamabata S; Rehabilitation Unit, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yukawa A; Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Teramukai S; Department of Biostatistics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Imai K; Department for Medical Innovation and Translational Medical Science, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan.
Ito-Ihara T; The Clinical and Translational Research Center, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tao M; The Clinical and Translational Research Center, University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Higashi Y; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Ishigami T; Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
Fukumoto Y; Department of Internal Medicine, Division of Cardiovascular Medicine, Kurume University School of Medicine, Fukuoka, Japan.
Kuwahara K; Department of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Matoba S; Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Contemp Clin Trials Commun ; 17: 100542, 2020 Mar.

Article em En | MEDLINE | ID: mdl-32072074

Palavras-chave

ASO, arteriosclerosis obliterans; Arteriosclerosis obliterans; BM-MNC, bone marrow-derived mononuclear cells; CLI, critical limb ischemia; CT, computed tomography; Critical limb ischemia; NIRS, near-infrared spectroscopy; NO, nitric oxide; Near-infrared spectroscopy; Optimal exercise therapy; PAD, peripheral artery disease; RHI, reactive hyperemia index; SPP, skin perfusion pressure; StO2, thenar tissue oxygen saturation; TAO, thromboangiitis obliterans; TOI, tissue oxygenation index; TcPO2, transcutaneous oxygen pressure; Therapeutic angiogenesis; Tissue muscle oxygen saturation; VAS, visual analogue scale; WIQ, walking impairment questionnaire; eNOS, endothelial nitric oxide synthase; nTHI, normalized tissue hemoglobin index; ΔHHb, change in deoxygenated hemoglobin concentration; ΔO2Hb, change in oxygenated hemoglobin concentration

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article