Clinical implementation of pharmacogenomics via a health system-wide research biobank: the University of Colorado experience.
Pharmacogenomics
; 21(6): 375-386, 2020 04.
Article
em En
| MEDLINE
| ID: mdl-32077359
ABSTRACT
In recent years, the genomics community has witnessed the growth of large research biobanks, which collect DNA samples for research purposes. Depending on how and where the samples are genotyped, biobanks also offer the potential opportunity to return actionable genomic results to the clinical setting. We developed a preemptive clinical pharmacogenomic implementation initiative via a health system-wide research biobank at the University of Colorado. Here, we describe how preemptive return of clinical pharmacogenomic results via a research biobank is feasible, particularly when coupled with strong institutional support to maximize the impact and efficiency of biobank resources, a multidisciplinary implementation team, automated clinical decision support tools, and proactive strategies to engage stakeholders early in the clinical decision support tool development process.
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Base de dados:
MEDLINE
Assunto principal:
Farmacogenética
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Bancos de Espécimes Biológicos
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Sistemas de Apoio a Decisões Clínicas
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Centros Médicos Acadêmicos
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Medicina de Precisão
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article