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Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences.
Kumar, Sushant; Warrell, Jonathan; Li, Shantao; McGillivray, Patrick D; Meyerson, William; Salichos, Leonidas; Harmanci, Arif; Martinez-Fundichely, Alexander; Chan, Calvin W Y; Nielsen, Morten Muhlig; Lochovsky, Lucas; Zhang, Yan; Li, Xiaotong; Lou, Shaoke; Pedersen, Jakob Skou; Herrmann, Carl; Getz, Gad; Khurana, Ekta; Gerstein, Mark B.
Afiliação
  • Kumar S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
  • Warrell J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
  • Li S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
  • McGillivray PD; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA; Yale School of Medicine, Yale University, New Haven, CT 06510, USA.
  • Meyerson W; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Yale School of Medicine, Yale University, New Haven, CT 06510, USA.
  • Salichos L; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
  • Harmanci A; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Center for Precision Health, School of Biomedical Informatics, University of Texas Health Sciences Center, Houston, TX 77030, USA.
  • Martinez-Fundichely A; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York,
  • Chan CWY; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg 69120, Germany.
  • Nielsen MM; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark.
  • Lochovsky L; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
  • Zhang Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH 43210, USA; The Ohio State University Comprehensive Cancer Center (OSUCCC-James), Columbus, OH 43210, USA.
  • Li X; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.
  • Lou S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.
  • Pedersen JS; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark.
  • Herrmann C; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Health Data Science Unit, Medical Faculty Heidelberg and BioQuant, Heidelberg 69120, Germany.
  • Getz G; The Broad Institute of MIT and Harvard, Cambridge, MA 02124, USA; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129, USA; Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA.
  • Khurana E; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York,
  • Gerstein MB; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA; Department of Computer Science, Yale University, New Haven, CT 06511, USA. Electronic address: mark@gerstein
Cell ; 180(5): 915-927.e16, 2020 03 05.
Article em En | MEDLINE | ID: mdl-32084333

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Genômica / Mutação / Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Genômica / Mutação / Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article