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Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis.
Wang, Yu-Ling; Wu, Wei; Su, Yong-Nan; Ai, Zhi-Peng; Mou, Han-Chuan; Wan, Luo-Sheng; Luo, Ying; Qiu, Ming-Hua; Zhang, Ji-Hong.
Afiliação
  • Wang YL; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.
  • Wu W; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.
  • Su YN; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.
  • Ai ZP; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.
  • Mou HC; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.
  • Wan LS; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
  • Luo Y; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.
  • Qiu MH; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China. Electronic address: mhchiu@mail.kib.ac.cn.
  • Zhang JH; Medical School, Kunming University of Science and Technology, Kunming 650500, PR China. Electronic address: zhjihong2000@kust.edu.cn.
Phytomedicine ; 68: 153187, 2020 Mar.
Article em En | MEDLINE | ID: mdl-32097779
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Buxus / 20-alfa-Di-Hidroprogesterona / Fatores de Transcrição de Choque Térmico / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Buxus / 20-alfa-Di-Hidroprogesterona / Fatores de Transcrição de Choque Térmico / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article