Wilms tumor 1 regulates lipid accumulation in human endometrial stromal cells during decidualization.

Tamura, Isao; Takagi, Haruka; Doi-Tanaka, Yumiko; Shirafuta, Yuichiro; Mihara, Yumiko; Shinagawa, Masahiro; Maekawa, Ryo; Taketani, Toshiaki; Sato, Shun; Tamura, Hiroshi; Sugino, Norihiro

Tamura, Isao; Takagi, Haruka; Doi-Tanaka, Yumiko; Shirafuta, Yuichiro; Mihara, Yumiko; Shinagawa, Masahiro; Maekawa, Ryo; Taketani, Toshiaki; Sato, Shun; Tamura, Hiroshi; Sugino, Norihiro.

Afiliação

Tamura I; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan isao@yamaguchi-u.ac.jp.
Takagi H; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Doi-Tanaka Y; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Shirafuta Y; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Mihara Y; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Shinagawa M; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Maekawa R; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Taketani T; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Sato S; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Tamura H; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
Sugino N; Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.

J Biol Chem ; 295(14): 4673-4683, 2020 04 03.

Article em En | MEDLINE | ID: mdl-32098869

Assuntos

Metabolismo dos Lipídeos; Proteínas WT1/metabolismo; Adulto; Células Cultivadas; AMP Cíclico/metabolismo; Proteína 1 de Resposta de Crescimento Precoce/metabolismo; Endométrio/citologia; Feminino; Regulação da Expressão Gênica; Humanos; Proteína 1 de Ligação a Fator de Crescimento Semelhante à Insulina/genética; Proteína 1 de Ligação a Fator de Crescimento Semelhante à Insulina/metabolismo; Pessoa de Meia-Idade; Regiões Promotoras Genéticas; Ligação Proteica; Interferência de RNA; RNA Interferente Pequeno/metabolismo; Receptores de LDL/antagonistas & inibidores; Receptores de LDL/genética; Receptores de LDL/metabolismo; Células Estromais/citologia; Células Estromais/metabolismo; Proteínas WT1/antagonistas & inibidores; Proteínas WT1/genética

Palavras-chave

Wilms tumor 1 (WT1); cell differentiation; cyclic AMP (cAMP); decidualization; endometrial stromal cells (ESCs); gene regulation; lipid droplet; lipid metabolism; pregnancy; very low-density lipoprotein receptor (VLDLR)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas WT1 / Metabolismo dos Lipídeos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas WT1 / Metabolismo dos Lipídeos Idioma: En Ano de publicação: 2020 Tipo de documento: Article