Stabilizing synthetic DNA for long-term data storage with earth alkaline salts.
Chem Commun (Camb)
; 56(25): 3613-3616, 2020 Mar 28.
Article
em En
| MEDLINE
| ID: mdl-32107514
ABSTRACT
Rapid aging tests (70 °C, 50% RH) of solid state DNA dried in the presence of various salt formulations, showed the strong stabilizing effect of calcium phosphate, calcium chloride and magnesium chloride, even at high DNA loadings (>20 wt%). A DNA-based digital information storage system utilizing the stabilizing effect of MgCl2 was tested by storing a DNA file, encoding 115 kB of digital data, and the successful readout of the file by sequencing after accelerated aging.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cloreto de Cálcio
/
Fosfatos de Cálcio
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DNA
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Cloreto de Magnésio
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Armazenamento e Recuperação da Informação
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article