MiR-139-5p/SLC7A11 inhibits the proliferation, invasion and metastasis of pancreatic carcinoma via PI3K/Akt signaling pathway.

Zhu, Jin-Hui; De Mello, Ramon Andrade; Yan, Qiu-Liang; Wang, Jian-Wei; Chen, Yan; Ye, Qing-Huang; Wang, Zhi-Jiang; Tang, Hai-Jun; Huang, Tao

Zhu, Jin-Hui; De Mello, Ramon Andrade; Yan, Qiu-Liang; Wang, Jian-Wei; Chen, Yan; Ye, Qing-Huang; Wang, Zhi-Jiang; Tang, Hai-Jun; Huang, Tao.

Afiliação

Zhu JH; Department of General Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China. Electronic address: 2512016@zju.edu.cn.
De Mello RA; Department of Biomedical Sciences & Medicine, University of Algarve, Faro, Portugal.
Yan QL; Department of General Surgery, Jinhua People's Hospital, Jinhua 321000, China.
Wang JW; Department of Surgical Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Chen Y; Department of General Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Ye QH; Department of General Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Wang ZJ; Department of General Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Tang HJ; Department of General Surgery, Shaoxing People's Hospital, Shaoxing 312000, China. Electronic address: tanghaijun.1988@163.com.
Huang T; Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: tohuangtao@126.com.

Biochim Biophys Acta Mol Basis Dis ; 1866(6): 165747, 2020 06 01.

Article em En | MEDLINE | ID: mdl-32109492

Assuntos

Sistema y+ de Transporte de Aminoácidos/genética; Carcinogênese/genética; MicroRNAs/genética; Neoplasias Pancreáticas/genética; Animais; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/genética; Feminino; Regulação Neoplásica da Expressão Gênica/genética; Xenoenxertos; Humanos; Masculino; Camundongos; Pessoa de Meia-Idade; Invasividade Neoplásica/genética; Invasividade Neoplásica/patologia; Metástase Neoplásica; Proteína Oncogênica v-akt/genética; Neoplasias Pancreáticas/patologia; Fosfatidilinositol 3-Quinases/genética; Transdução de Sinais/genética; Neoplasias Pancreáticas

Palavras-chave

Invasion and metastasis; Pancreatic cancer; Proliferation; SLC7A11; miR-139-5p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Sistema y/ de Transporte de Aminoácidos / MicroRNAs / Carcinogênese Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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