Round Cell Sarcoma with EWSR1-PATZ1 Gene Fusion in the Neck: Case Report and Review of the Literature.
Laryngoscope
; 130(12): E833-E836, 2020 12.
Article
em En
| MEDLINE
| ID: mdl-32134119
ABSTRACT
EWSR1-PATZ1 is a rare gene fusion recently recognized to occur in round and spindle cell sarcomas. To date, fewer than 20 cases have been described in the literature. However, no dedicated case reports have detailed its presentation in the head and neck region. We recently cared for a 52-year-old woman with an isolated, single right level 5A cervical mass. Excisional biopsy at an external hospital revealed pathology results consistent with EWSR1-PATZ1 polyphenotypic round and spindle cell sarcoma. The patient subsequently underwent surgical excision of the tumor and right neck lymph node dissection followed by adjuvant chemoradiation. Laryngoscope, 2020.
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MEDLINE
Assunto principal:
Proteínas Repressoras
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Sarcoma
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Proteína EWS de Ligação a RNA
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Fatores de Transcrição Kruppel-Like
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Fusão Gênica
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Neoplasias de Cabeça e Pescoço
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article