SGLT2 Inhibitor-Induced Sympathoinhibition: A Novel Mechanism for Cardiorenal Protection.

Herat, Lakshini Y; Magno, Aaron L; Rudnicka, Caroline; Hricova, Jana; Carnagarin, Revathy; Ward, Natalie C; Arcambal, Angelique; Kiuchi, Marcio G; Head, Geoff A; Schlaich, Markus P; Matthews, Vance B.

Afiliação

Herat LY; Dobney Hypertension Centre, School of Biomedical Science, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia.
Magno AL; Research Centre, Royal Perth Hospital, Perth, Australia.
Rudnicka C; Research Centre, Royal Perth Hospital, Perth, Australia.
Hricova J; Dobney Hypertension Centre, School of Biomedical Science, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia.
Carnagarin R; Dobney Hypertension Centre, School of Medicine, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia.
Ward NC; School of Medicine, Royal Perth Hospital, University of Western Australia, Perth, Australia.
Arcambal A; School of Public Health, Curtin University, Perth, Australia.
Kiuchi MG; Curtin Health Innovation Research Institute, Curtin University, Perth, Australia.
Head GA; School of Medicine, Royal Perth Hospital, University of Western Australia, Perth, Australia.
Schlaich MP; Université de La Réunion, Saint-Denis, Réunion, France.
Matthews VB; Dobney Hypertension Centre, School of Medicine, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia.

JACC Basic Transl Sci ; 5(2): 169-179, 2020 Feb.

Article em En | MEDLINE | ID: mdl-32140623

Palavras-chave

6-OHDA, 6-hydroxydopamine; DBP, diastolic blood pressure; ELISA, enzyme-linked immunosorbent assay; HFD, high-fat diet; MAP, mean arterial pressure; SBP, systolic blood pressure; SCFA, short-chain fatty acid; SGLT2; SGLT2, sodium glucose cotransporter 2; SNS, sympathetic nervous system; denervation; heart; hypertension; kidney; sympathetic nervous system

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article