Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study.

Vistoli, Giulio; Aldini, Giancarlo; Fumagalli, Laura; Dallanoce, Clelia; Angeli, Andrea; Supuran, Claudiu T

Vistoli, Giulio; Aldini, Giancarlo; Fumagalli, Laura; Dallanoce, Clelia; Angeli, Andrea; Supuran, Claudiu T.

Afiliação

Vistoli G; Department of Pharmaceutical Sciences, University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
Aldini G; Department of Pharmaceutical Sciences, University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
Fumagalli L; Department of Pharmaceutical Sciences, University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
Dallanoce C; Department of Pharmaceutical Sciences, University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
Angeli A; Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Supuran CT; Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

Int J Mol Sci ; 21(5)2020 Mar 04.

Article em En | MEDLINE | ID: mdl-32143488

Assuntos

Anidrases Carbônicas/metabolismo; Carnosina/química; Dipeptídeos/química; Histidina/química; Anidrase Carbônica I/metabolismo; Anidrase Carbônica II/metabolismo; Anidrase Carbônica IX/metabolismo; Anidrase Carbônica V/metabolismo; Carnosina/análogos & derivados; Quelantes/farmacologia; Humanos; Cinética; Modelos Moleculares; Domínios Proteicos; Prótons; Software

Palavras-chave

activator; carbonic anhydrase; carnosine; dipeptide; histidine; proton shuttling

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carnosina / Anidrases Carbônicas / Dipeptídeos / Histidina Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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