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Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Pichkur, Evgeny B; Paleskava, Alena; Tereshchenkov, Andrey G; Kasatsky, Pavel; Komarova, Ekaterina S; Shiriaev, Dmitrii I; Bogdanov, Alexey A; Dontsova, Olga A; Osterman, Ilya A; Sergiev, Petr V; Polikanov, Yury S; Myasnikov, Alexander G; Konevega, Andrey L.
Afiliação
  • Pichkur EB; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC "Kurchatov Institute," Gatchina, 188300, Russia.
  • Paleskava A; National Research Center "Kurchatov Institute," Moscow, 123182, Russia.
  • Tereshchenkov AG; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC "Kurchatov Institute," Gatchina, 188300, Russia.
  • Kasatsky P; Peter the Great St. Petersburg Polytechnic University, Saint Petersburg, 195251, Russia.
  • Komarova ES; Department of Chemistry and A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
  • Shiriaev DI; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of NRC "Kurchatov Institute," Gatchina, 188300, Russia.
  • Bogdanov AA; Department of Bioengineering and Bioinformatics and A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
  • Dontsova OA; Skolkovo Institute of Science and Technology, Skolkovo, Moscow region, 143025, Russia.
  • Osterman IA; Department of Chemistry and A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
  • Sergiev PV; Department of Chemistry and A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
  • Polikanov YS; Department of Chemistry and A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
  • Myasnikov AG; Skolkovo Institute of Science and Technology, Skolkovo, Moscow region, 143025, Russia.
  • Konevega AL; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia.
RNA ; 26(6): 715-723, 2020 06.
Article em En | MEDLINE | ID: mdl-32144191
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribossomos / Inibidores da Síntese de Proteínas / Eritromicina / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribossomos / Inibidores da Síntese de Proteínas / Eritromicina / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article