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Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients.
Arshad, Usman; Ploylearmsaeng, Su-Arpa; Karlsson, Mats O; Doroshyenko, Oxana; Langer, Dorothee; Schömig, Edgar; Kunze, Sabine; Güner, Semih A; Skripnichenko, Roman; Ullah, Sami; Jaehde, Ulrich; Fuhr, Uwe; Jetter, Alexander; Taubert, Max.
Afiliação
  • Arshad U; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany. arshad_u@outlook.com.
  • Ploylearmsaeng SA; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden. arshad_u@outlook.com.
  • Karlsson MO; Institute of Pharmacy, Clinical Pharmacy, University of Bonn, Bonn, Germany. arshad_u@outlook.com.
  • Doroshyenko O; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Langer D; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
  • Schömig E; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Kunze S; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Güner SA; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Skripnichenko R; Department of Radiotherapy, University Hospital Cologne, Cologne, Germany.
  • Ullah S; Department of Radiotherapy, University Hospital Cologne, Cologne, Germany.
  • Jaehde U; Department of Radiotherapy, University Hospital Cologne, Cologne, Germany.
  • Fuhr U; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Jetter A; Institute of Pharmacy, Clinical Pharmacy, University of Bonn, Bonn, Germany.
  • Taubert M; Institute of Pharmacy, Clinical Pharmacy, University of Bonn, Bonn, Germany.
Cancer Chemother Pharmacol ; 85(4): 711-722, 2020 04.
Article em En | MEDLINE | ID: mdl-32152679
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Mieloides / Fluoruracila / Neoplasias Gastrointestinais / Modelos Biológicos / Antimetabólitos Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Mieloides / Fluoruracila / Neoplasias Gastrointestinais / Modelos Biológicos / Antimetabólitos Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article