<i>In silico</i> Investigations of the Mode of Action of Novel Colchicine Derivatives Targeting ß-Tubulin Isotypes: A Search for a Selective and Specific ß-III Tubulin Ligand.

Pallante, Lorenzo; Rocca, Antonio; Klejborowska, Greta; Huczynski, Adam; Grasso, Gianvito; Tuszynski, Jack A; Deriu, Marco A

In silico Investigations of the Mode of Action of Novel Colchicine Derivatives Targeting ß-Tubulin Isotypes: A Search for a Selective and Specific ß-III Tubulin Ligand.

Pallante, Lorenzo; Rocca, Antonio; Klejborowska, Greta; Huczynski, Adam; Grasso, Gianvito; Tuszynski, Jack A; Deriu, Marco A.

Afiliação

Pallante L; PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Rocca A; PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Klejborowska G; Department of Chemistry, Adam Mickiewicz University, Poznan, Poland.
Huczynski A; Department of Chemistry, Adam Mickiewicz University, Poznan, Poland.
Grasso G; Dalle Molle Institute for Artificial Intelligence (IDSIA), University of Applied Sciences of Southern Switzerland (SUPSI), University of Italian Switzerland (USI), Manno, Switzerland.
Tuszynski JA; PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Deriu MA; Department of Oncology, University of Alberta, Edmonton, AB, Canada.

Front Chem ; 8: 108, 2020.

Article em En | MEDLINE | ID: mdl-32154219