E-cigarettes and their impact on health: from pharmacology to clinical implications.
Pol Arch Intern Med
; 130(7-8): 668-675, 2020 08 27.
Article
em En
| MEDLINE
| ID: mdl-32155137
ABSTRACT
Worldwide, cigarette smoking is the major cause of premature mortality and diseases that can be prevented. Given that people continue smoking despite associated health risks, delivering nicotine without combustion should be considered a valuable and much less harmful way to reduce the public health burden caused by smoking. Ecigarettes could play such a role if they were proven to be less harmful than combustible cigarettes. Although the number of clinical trials and human studies assessing the safety of ecigarettes is limited, numerous in vitro and in vivo studies reported on the potential harmful effects of the aerosol generated from ecigarettes. This article reviews the results of major clinical trials and laboratory studies with regard to cancer as well as cardiovascular and respiratory risk associated with the use of ecigarettes. Additionally, it also discusses the potential application of ecigarettes as smoking cessation tools. Most studies have indicated so far that ecigarettes are less harmful, but this applies only to smokers who completely switched to ecigarettes. In the opinion of the authors, good-quality research is crucial to establish the tolerance, safety, efficacy, and harm reduction potential of new technologies. Considering a significant role that physicians and other health providers play in helping smokers, there is an urgent need for evidencebased guidelines and recommendations for clinical practitioners on potential benefits and risks of ecigarette use.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Abandono do Hábito de Fumar
/
Sistemas Eletrônicos de Liberação de Nicotina
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article